In a Reddit post, AMD has acknowledged that some of its 500-series motherboards suffer from a USB connection issue wherein the device gets frequently disconnected, causing it to lose power and therefore stop working. This issue is most commonly reproducible with dual-USB keyboards, high-end headsets as well as VR headsets.
Although in some cases this can be fixed by switching from PCI Gen 4 to Gen 3 in the BIOS or by disabling the “C-States”, these don’t always work, and mostly just reduce the frequency of the issue.
AMD is aware of reports that a small number of users are experiencing intermittent USB connectivity issues reported on 500 Series chipsets. We have been analyzing the root cause and at this time, we would like to request the community’s assistance with a small selection of additional hardware configurations. Over the next few days, some r/Amd users may be contacted directly by an AMD representative (u/AMDOfficial) via Reddit’s PM system with a request for more information.
This request may include detailed hardware configurations, steps to reproduce the issue, specific logs, and other system information pertinent to verifying our development efforts. We will provide an update when we have more details to share. Customers facing issues are always encouraged to raise an Online Service Request with AMD customer support; this enables us to find correlations and compare notes across support claims.Source
We expect AMD to launch a firmware update (AGESA) in the future that fixes this problem as there are quite a few users experiencing it.